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UFL1 promotes histone H4 ufmylation and ATM activation

The ataxia-telangiectasia mutated (ATM) kinase, an upstream kinase of the DNA damage response (DDR), is rapidly activated following DNA damage, and phosphorylates its downstream targets to launch DDR signaling. However, the mechanism of ATM activation is still not completely understood. Here we repo...

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Detalles Bibliográficos
Autores principales: Qin, Bo, Yu, Jia, Nowsheen, Somaira, Wang, Minghui, Tu, Xinyi, Liu, Tongzheng, Li, Honglin, Wang, Liewei, Lou, Zhenkun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423285/
https://www.ncbi.nlm.nih.gov/pubmed/30886146
http://dx.doi.org/10.1038/s41467-019-09175-0