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A critical regulator of Bcl2 revealed by systematic transcript discovery of lncRNAs associated with T-cell differentiation

Normal T-cell differentiation requires a complex regulatory network which supports a series of maturation steps, including lineage commitment, T-cell receptor (TCR) gene rearrangement, and thymic positive and negative selection. However, the underlying molecular mechanisms are difficult to assess du...

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Detalles Bibliográficos
Autores principales: Saadi, Wiam, Kermezli, Yasmina, Dao, Lan T. M., Mathieu, Evelyne, Santiago-Algarra, David, Manosalva, Iris, Torres, Magali, Belhocine, Mohamed, Pradel, Lydie, Loriod, Beatrice, Aribi, Mourad, Puthier, Denis, Spicuglia, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423290/
https://www.ncbi.nlm.nih.gov/pubmed/30886319
http://dx.doi.org/10.1038/s41598-019-41247-5