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Inactivation of a CRF-dependent amygdalofugal pathway reverses addiction-like behaviors in alcohol-dependent rats

The activation of a neuronal ensemble in the central nucleus of the amygdala (CeA) during alcohol withdrawal has been hypothesized to induce high levels of alcohol drinking in dependent rats. In the present study we describe that the CeA neuronal ensemble that is activated by withdrawal from chronic...

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Detalles Bibliográficos
Autores principales: de Guglielmo, Giordano, Kallupi, Marsida, Pomrenze, Matthew B., Crawford, Elena, Simpson, Sierra, Schweitzer, Paul, Koob, George F., Messing, Robert O., George, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423296/
https://www.ncbi.nlm.nih.gov/pubmed/30886240
http://dx.doi.org/10.1038/s41467-019-09183-0