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Targeting the Antibody Checkpoints to Enhance Cancer Immunotherapy–Focus on FcγRIIB

Immunotherapy with therapeutic antibodies has increased survival for patients with hematologic and solid cancers. Still, a significant fraction of patients fails to respond to therapy or acquire resistance. Understanding and overcoming mechanisms of resistance to antibody drugs, and in particular th...

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Detalles Bibliográficos
Autores principales: Teige, Ingrid, Mårtensson, Linda, Frendéus, Björn L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423481/
https://www.ncbi.nlm.nih.gov/pubmed/30930905
http://dx.doi.org/10.3389/fimmu.2019.00481