Chemotherapy Modulates Endocrine Therapy-Related Resistance Mutations in Metastatic Breast Cancer

PURPOSE: Accumulation of PIK3CA, ESR1, and GATA3 mutations results in resistance to endocrine therapy in breast cancer patients; however, the response of these genes to chemotherapy is unclear. Therefore, we sought to evaluate the genetic response of circulating tumor DNA (ctDNA) to chemotherapy in...

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Detalles Bibliográficos
Autores principales: Zhou, Dabo, Ouyang, Quchang, Liu, Liping, Liu, Jingyu, Tang, Yu, Xiao, Mengjia, Wang, Yikai, He, Qiongzhi, Hu, Zhe-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423490/
https://www.ncbi.nlm.nih.gov/pubmed/30893632
http://dx.doi.org/10.1016/j.tranon.2019.02.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423490/
https://www.ncbi.nlm.nih.gov/pubmed/30893632
http://dx.doi.org/10.1016/j.tranon.2019.02.014

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