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Glucose-Regulated Protein 78 Signaling Regulates Hypoxia-Induced Epithelial–Mesenchymal Transition in A549 Cells

Objective: Metastasis and therapeutic resistance are the major determinants of lung cancer progression and high mortality. Epithelial–mesenchymal transition (EMT) plays a key role in the metastasis and therapeutic resistance. Highly expressed glucose-regulated protein 78 (GRP78) is a poor prognostic...

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Detalles Bibliográficos
Autores principales: Sun, Ling-Ling, Chen, Chang-Ming, Zhang, Jue, Wang, Jing, Yang, Cai-Zhi, Lin, Li-Zhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423493/
https://www.ncbi.nlm.nih.gov/pubmed/30931255
http://dx.doi.org/10.3389/fonc.2019.00137