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Age- and brain region-associated alterations of cerebral blood flow in early Alzheimer's disease assessed in AβPP(SWE)/PS1(ΔE9) transgenic mice using arterial spin labeling

It has been suggested that cerebral blood flow (CBF) alterations may be involved in the pathogenesis of Alzheimer's disease (AD). However, how CBF changes with age has not been detailed in AD, particularly in its early stages. The objective of the present study was to evaluate CBF in four brain...

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Detalles Bibliográficos
Autores principales: Guo, Yapei, Li, Xueyuan, Zhang, Min, Chen, Ningning, Wu, Shitao, Lei, Jianfeng, Wang, Zhanjing, Wang, Renzhi, Wang, Jianping, Liu, Hengfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423566/
https://www.ncbi.nlm.nih.gov/pubmed/30816468
http://dx.doi.org/10.3892/mmr.2019.9950