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The LANCA three-component reaction to highly substituted β-ketoenamides – versatile intermediates for the synthesis of functionalized pyridine, pyrimidine, oxazole and quinoxaline derivatives

The LANCA three-component reaction of lithiated alkoxyallenes LA, nitriles N and carboxylic acids CA leads to β-ketoenamides KE in good to excellent yields. The scope of this reaction is very broad and almost all types of nitriles and carboxylic acids have successfully been used. The alkoxy group in...

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Detalles Bibliográficos
Autores principales: Lechel, Tilman, Kumar, Roopender, Bera, Mrinal K, Zimmer, Reinhold, Reissig, Hans-Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423578/
https://www.ncbi.nlm.nih.gov/pubmed/30931007
http://dx.doi.org/10.3762/bjoc.15.61