Catalyst-free assembly of giant tris(heteroaryl)methanes: synthesis of novel pharmacophoric triads and model sterically crowded tris(heteroaryl/aryl)methyl cation salts

A series of giant tris(heteroaryl)methanes are easily assembled by one-pot three-component synthesis by simple reflux in ethanol without catalyst or additives. Diversely substituted indoles (Ar(1)) react with quinoline aldehydes, quinolone aldehydes, chromone aldehydes, and fluorene aldehydes (Ar(2)...

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Detalles Bibliográficos
Autores principales: Abonia, Rodrigo, Gutiérrez, Luisa F, Insuasty, Braulio, Quiroga, Jairo, Laali, Kenneth K, Zhao, Chunqing, Borosky, Gabriela L, Horwitz, Samantha M, Bunge, Scott D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2019
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423583/
https://www.ncbi.nlm.nih.gov/pubmed/30931006
http://dx.doi.org/10.3762/bjoc.15.60

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423583/
https://www.ncbi.nlm.nih.gov/pubmed/30931006
http://dx.doi.org/10.3762/bjoc.15.60

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