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A Practical Review of Proteasome Pharmacology

The ubiquitin proteasome system (UPS) degrades individual proteins in a highly regulated fashion and is responsible for the degradation of misfolded, damaged, or unneeded cellular proteins. During the past 20 years, investigators have established a critical role for the UPS in essentially every cell...

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Detalles Bibliográficos
Autores principales: Thibaudeau, Tiffany A., Smith, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423620/
https://www.ncbi.nlm.nih.gov/pubmed/30867233
http://dx.doi.org/10.1124/pr.117.015370