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Nonhuman Primates and Humanized Mice for Studies of HIV-1 Integrase Inhibitors: A Review
Since the discovery of the first inhibitors of HIV replication, drug resistance has been a major problem in HIV therapy due in part to the high mutation rate of HIV. Therefore, the development of a predictive animal model is important to identify impending resistance mutations and to possibly inform...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Pathogens and Immunity
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423640/ https://www.ncbi.nlm.nih.gov/pubmed/30993244 http://dx.doi.org/10.20411/pai.v1i1.104 |