Merger of dynamic two-photon and phosphorescence lifetime microscopy reveals dependence of lymphocyte motility on oxygen in solid and hematological tumors

BACKGROUND: Low availability of oxygen in tumors contributes to the hostility of the tumor microenvironment toward the immune system. However, the dynamic relationship between local oxygen levels and the immune surveillance of tumors by tumor infiltrating T-lymphocytes (TIL) remains unclear. This si...

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Detalles Bibliográficos
Autores principales: Rytelewski, Mateusz, Haryutyunan, Karine, Nwajei, Felix, Shanmugasundaram, Meenakshi, Wspanialy, Patrick, Zal, M. Anna, Chen, Chao-Hsien, El Khatib, Mirna, Plunkett, Shane, Vinogradov, Sergei A., Konopleva, Marina, Zal, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423744/
https://www.ncbi.nlm.nih.gov/pubmed/30885258
http://dx.doi.org/10.1186/s40425-019-0543-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423744/
https://www.ncbi.nlm.nih.gov/pubmed/30885258
http://dx.doi.org/10.1186/s40425-019-0543-y

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