MEF2A alters the proliferation, inflammation-related gene expression profiles and its silencing induces cellular senescence in human coronary endothelial cells

BACKGROUND: Myocyte enhancer factor 2A (MEF2A) plays an important role in cell proliferation, differentiation and survival. Functional deletion or mutation in MEF2A predisposes individuals to cardiovascular disease mainly caused by vascular endothelial dysfunction. However, the effect of the inhibit...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiong, Yujuan, Wang, Lin, Jiang, Wenyi, Pang, Lihua, Liu, Weihua, Li, Aiqun, Zhong, Yun, Ou, Wenchao, Liu, Benrong, Liu, Shi-ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423757/
https://www.ncbi.nlm.nih.gov/pubmed/30885136
http://dx.doi.org/10.1186/s12867-019-0125-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423757/
https://www.ncbi.nlm.nih.gov/pubmed/30885136
http://dx.doi.org/10.1186/s12867-019-0125-z

Ejemplares similares