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Altered bioavailability of epoxyeicosatrienoic acids is associated with conduit artery endothelial dysfunction in type 2 diabetic patients

BACKGROUND: This pathophysiological study addressed the hypothesis that soluble epoxide hydrolase (sEH), which metabolizes the vasodilator and anti-inflammatory epoxyeicosatrienoic acids (EETs) to dihydroxyeicosatrienoic acids (DHETs), contributes to conduit artery endothelial dysfunction in type 2...

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Detalles Bibliográficos
Autores principales: Duflot, Thomas, Moreau-Grangé, Lucile, Roche, Clothilde, Iacob, Michèle, Wils, Julien, Rémy-Jouet, Isabelle, Cailleux, Anne-Françoise, Leuillier, Matthieu, Renet, Sylvanie, Li, Dongyang, Morisseau, Christophe, Lamoureux, Fabien, Richard, Vincent, Prévost, Gaëtan, Joannidès, Robinson, Bellien, Jérémy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423843/
https://www.ncbi.nlm.nih.gov/pubmed/30885203
http://dx.doi.org/10.1186/s12933-019-0843-z