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Long-read based assembly and synteny analysis of a reference Drosophila subobscura genome reveals signatures of structural evolution driven by inversions recombination-suppression effects

BACKGROUND: Drosophila subobscura has long been a central model in evolutionary genetics. Presently, its use is hindered by the lack of a reference genome. To bridge this gap, here we used PacBio long-read technology, together with the available wealth of genetic marker information, to assemble and...

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Detalles Bibliográficos
Autores principales: Karageorgiou, Charikleia, Gámez-Visairas, Víctor, Tarrío, Rosa, Rodríguez-Trelles, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423853/
https://www.ncbi.nlm.nih.gov/pubmed/30885123
http://dx.doi.org/10.1186/s12864-019-5590-8