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Long-read based assembly and synteny analysis of a reference Drosophila subobscura genome reveals signatures of structural evolution driven by inversions recombination-suppression effects
BACKGROUND: Drosophila subobscura has long been a central model in evolutionary genetics. Presently, its use is hindered by the lack of a reference genome. To bridge this gap, here we used PacBio long-read technology, together with the available wealth of genetic marker information, to assemble and...
Autores principales: | Karageorgiou, Charikleia, Gámez-Visairas, Víctor, Tarrío, Rosa, Rodríguez-Trelles, Francisco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423853/ https://www.ncbi.nlm.nih.gov/pubmed/30885123 http://dx.doi.org/10.1186/s12864-019-5590-8 |
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