Short-term metabolic adjustments in Plasmodium falciparum counter hypoxanthine deprivation at the expense of long-term viability

BACKGROUND: The malarial parasite Plasmodium falciparum is an auxotroph for purines, which are required for nucleic acid synthesis during the intra-erythrocytic developmental cycle (IDC) of the parasite. The capabilities of the parasite and extent to which it can use compensatory mechanisms to adapt...

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Detalles Bibliográficos
Autores principales: Tewari, Shivendra G., Rajaram, Krithika, Schyman, Patric, Swift, Russell, Reifman, Jaques, Prigge, Sean T., Wallqvist, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423861/
https://www.ncbi.nlm.nih.gov/pubmed/30890151
http://dx.doi.org/10.1186/s12936-019-2720-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423861/
https://www.ncbi.nlm.nih.gov/pubmed/30890151
http://dx.doi.org/10.1186/s12936-019-2720-3

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