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Rationale for Combining Radiotherapy and Immune Checkpoint Inhibition for Patients With Hypoxic Tumors

In order to compensate for the increased oxygen consumption in growing tumors, tumors need angiogenesis and vasculogenesis to increase the supply. Insufficiency in this process or in the microcirculation leads to hypoxic tumor areas with a significantly reduced pO2, which in turn leads to alteration...

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Detalles Bibliográficos
Autores principales: Eckert, Franziska, Zwirner, Kerstin, Boeke, Simon, Thorwarth, Daniela, Zips, Daniel, Huber, Stephan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423917/
https://www.ncbi.nlm.nih.gov/pubmed/30930892
http://dx.doi.org/10.3389/fimmu.2019.00407