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Rationale for Combining Radiotherapy and Immune Checkpoint Inhibition for Patients With Hypoxic Tumors
In order to compensate for the increased oxygen consumption in growing tumors, tumors need angiogenesis and vasculogenesis to increase the supply. Insufficiency in this process or in the microcirculation leads to hypoxic tumor areas with a significantly reduced pO2, which in turn leads to alteration...
Autores principales: | Eckert, Franziska, Zwirner, Kerstin, Boeke, Simon, Thorwarth, Daniela, Zips, Daniel, Huber, Stephan M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423917/ https://www.ncbi.nlm.nih.gov/pubmed/30930892 http://dx.doi.org/10.3389/fimmu.2019.00407 |
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