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Inhibition of Notch1 Signaling Alleviates Endotoxin-Induced Inflammation Through Modulating Retinal Microglia Polarization

Microglial cells are resident immune cells and play an important role in various cerebral and retinal inflammatory diseases. Notch1 signaling is involved in the microglia polarization and the control of cerebral inflammatory reactions. However, its role in endotoxin-induced uveitis (EIU) remains unk...

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Detalles Bibliográficos
Autores principales: Cheng, Zhixing, Yang, Yao, Duan, Fang, Lou, Bingsheng, Zeng, Jieting, Huang, Yanqiao, Luo, Yan, Lin, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423918/
https://www.ncbi.nlm.nih.gov/pubmed/30930891
http://dx.doi.org/10.3389/fimmu.2019.00389