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Generate TALE/TALEN as Easily and Rapidly as Generating CRISPR
TALE has always had potential as a gene-editing and regulatory tool. However, with the advent of CRISPR/Cas9, an easier to use tool with the same function, TALE has recently been abandoned because of the time-consuming and low-efficiency process required for its construction. The off-target activity...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423989/ https://www.ncbi.nlm.nih.gov/pubmed/30923728 http://dx.doi.org/10.1016/j.omtm.2019.02.004 |