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Combined test versus logrank/Cox test in 50 randomised trials
BACKGROUND: The logrank test and the Cox proportional hazards model are routinely applied in the design and analysis of randomised controlled trials (RCTs) with time-to-event outcomes. Usually, sample size and power calculations assume proportional hazards (PH) of the treatment effect, i.e. the haza...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424007/ https://www.ncbi.nlm.nih.gov/pubmed/30885277 http://dx.doi.org/10.1186/s13063-019-3251-5 |