Human DNA polymerase delta is a pentameric holoenzyme with a dimeric p12 subunit

Human DNA polymerase delta (Polδ), a holoenzyme consisting of p125, p50, p68, and p12 subunits, plays an essential role in DNA replication, repair, and recombination. Herein, using multiple physicochemical and cellular approaches, we found that the p12 protein forms a dimer in solution. In vitro rec...

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Detalles Bibliográficos
Autores principales: Khandagale, Prashant, Peroumal, Doureradjou, Manohar, Kodavati, Acharya, Narottam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424025/
https://www.ncbi.nlm.nih.gov/pubmed/30885984
http://dx.doi.org/10.26508/lsa.201900323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424025/
https://www.ncbi.nlm.nih.gov/pubmed/30885984
http://dx.doi.org/10.26508/lsa.201900323

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