Cholinergic Deficit Induced by Central Administration of 192IgG-Saporin Is Associated With Activation of Microglia and Cell Loss in the Dorsal Hippocampus of Rats

Alzheimer’s disease (AD) is associated with degeneration of cholinergic neurons in the basal forebrain. Administration of the immunotoxin 192IgG-saporin to rats, an animal model of AD, leads to degeneration of cholinergic neurons in the medial septal area. In the present study, cholinergic cell deat...

Descripción completa

Detalles Bibliográficos
Autores principales: Dobryakova, Yulia V., Volobueva, Maria N., Manolova, Anna O., Medvedeva, Tatiana M., Kvichansky, Alexey A., Gulyaeva, Natalia V., Markevich, Vlamidir A., Stepanichev, Mikhail Yu., Bolshakov, Alexey P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424051/
https://www.ncbi.nlm.nih.gov/pubmed/30930730
http://dx.doi.org/10.3389/fnins.2019.00146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424051/
https://www.ncbi.nlm.nih.gov/pubmed/30930730
http://dx.doi.org/10.3389/fnins.2019.00146

Ejemplares similares