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Treatment of Intervertebral Disk Disease by the Administration of mRNA Encoding a Cartilage-Anabolic Transcription Factor

Intervertebral disk (IVD) degeneration is often associated with severity of lower back pain. IVD core is an avascular, highly hydrated tissue composed of type II collagen, glycosaminoglycans, and proteoglycans. The disk degeneration is not only a destruction of IVD structure but also is related to a...

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Detalles Bibliográficos
Autores principales: Lin, Chin-Yu, Crowley, Samuel Thomas, Uchida, Satoshi, Komaki, Yuji, Kataoka, Kazunori, Itaka, Keiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424144/
https://www.ncbi.nlm.nih.gov/pubmed/30889482
http://dx.doi.org/10.1016/j.omtn.2019.02.012