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Treatment of Intervertebral Disk Disease by the Administration of mRNA Encoding a Cartilage-Anabolic Transcription Factor
Intervertebral disk (IVD) degeneration is often associated with severity of lower back pain. IVD core is an avascular, highly hydrated tissue composed of type II collagen, glycosaminoglycans, and proteoglycans. The disk degeneration is not only a destruction of IVD structure but also is related to a...
Autores principales: | Lin, Chin-Yu, Crowley, Samuel Thomas, Uchida, Satoshi, Komaki, Yuji, Kataoka, Kazunori, Itaka, Keiji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424144/ https://www.ncbi.nlm.nih.gov/pubmed/30889482 http://dx.doi.org/10.1016/j.omtn.2019.02.012 |
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