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Myeloperoxidase inhibition in mice alters atherosclerotic lesion composition

Myeloperoxidase (MPO) is a highly abundant protein within the neutrophil that is associated with lipoprotein oxidation, and increased plasma MPO levels are correlated with poor prognosis after myocardial infarct. Thus, MPO inhibitors have been developed for the treatment of heart failure and acute c...

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Detalles Bibliográficos
Autores principales: Roth Flach, Rachel J., Su, Chunyan, Bollinger, Eliza, Cortes, Christian, Robertson, Andrew W., Opsahl, Alan C., Coskran, Timothy M., Maresca, Kevin P., Keliher, Edmund J., Yates, Phillip D., Kim, Albert M., Kalgutkar, Amit S., Buckbinder, Leonard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424399/
https://www.ncbi.nlm.nih.gov/pubmed/30889221
http://dx.doi.org/10.1371/journal.pone.0214150