An ABCA4 loss-of-function mutation causes a canine form of Stargardt disease

Autosomal recessive retinal degenerative diseases cause visual impairment and blindness in both humans and dogs. Currently, no standard treatment is available, but pioneering gene therapy-based canine models have been instrumental for clinical trials in humans. To study a novel form of retinal degen...

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Detalles Bibliográficos
Autores principales: Mäkeläinen, Suvi, Gòdia, Marta, Hellsand, Minas, Viluma, Agnese, Hahn, Daniela, Makdoumi, Karim, Zeiss, Caroline J., Mellersh, Cathryn, Ricketts, Sally L., Narfström, Kristina, Hallböök, Finn, Ekesten, Björn, Andersson, Göran, Bergström, Tomas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424408/
https://www.ncbi.nlm.nih.gov/pubmed/30889179
http://dx.doi.org/10.1371/journal.pgen.1007873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424408/
https://www.ncbi.nlm.nih.gov/pubmed/30889179
http://dx.doi.org/10.1371/journal.pgen.1007873

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