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Multiple functional neurosteroid binding sites on GABA(A) receptors

Neurosteroids are endogenous modulators of neuronal excitability and nervous system development and are being developed as anesthetic agents and treatments for psychiatric diseases. While gamma amino-butyric acid Type A (GABA(A)) receptors are the primary molecular targets of neurosteroid action, th...

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Detalles Bibliográficos
Autores principales: Chen, Zi-Wei, Bracamontes, John R., Budelier, Melissa M., Germann, Allison L., Shin, Daniel J., Kathiresan, Krishnan, Qian, Ming-Xing, Manion, Brad, Cheng, Wayland W. L., Reichert, David E., Akk, Gustav, Covey, Douglas F., Evers, Alex S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424464/
https://www.ncbi.nlm.nih.gov/pubmed/30845142
http://dx.doi.org/10.1371/journal.pbio.3000157