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An enriched network motif family regulates multistep cell fate transitions with restricted reversibility

Multistep cell fate transitions with stepwise changes of transcriptional profiles are common to many developmental, regenerative and pathological processes. The multiple intermediate cell lineage states can serve as differentiation checkpoints or branching points for channeling cells to more than on...

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Detalles Bibliográficos
Autores principales: Ye, Yujie, Kang, Xin, Bailey, Jordan, Li, Chunhe, Hong, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424469/
https://www.ncbi.nlm.nih.gov/pubmed/30845219
http://dx.doi.org/10.1371/journal.pcbi.1006855