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An enriched network motif family regulates multistep cell fate transitions with restricted reversibility
Multistep cell fate transitions with stepwise changes of transcriptional profiles are common to many developmental, regenerative and pathological processes. The multiple intermediate cell lineage states can serve as differentiation checkpoints or branching points for channeling cells to more than on...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424469/ https://www.ncbi.nlm.nih.gov/pubmed/30845219 http://dx.doi.org/10.1371/journal.pcbi.1006855 |