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Rabbit Model of Intra-Arterial Chemotherapy Toxicity Demonstrates Retinopathy and Vasculopathy Related to Drug and Dose, Not Procedure or Approach

PURPOSE: To use our intra-arterial chemotherapy (IAC) rabbit model to assess the impact of IAC procedure, drug, dose, and choice of technique on ocular structure and function, to study the nature and etiology of IAC toxicity, and to compare to observations in patients. METHODS: Rabbits received IAC...

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Detalles Bibliográficos
Autores principales: Daniels, Anthony B., Froehler, Michael T., Nunnally, Amy H., Pierce, Janene M., Bozic, Ivan, Stone, Cameron A., Santapuram, Pranav R., Tao, Yuankai K., Boyd, Kelli L., Himmel, Lauren E., Chen, Sheau-chiann, Du, Liping, Friedman, Debra L., Richmond, Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424472/
https://www.ncbi.nlm.nih.gov/pubmed/30882851
http://dx.doi.org/10.1167/iovs.18-25346