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Senecavirus A 3C Protease Mediates Host Cell Apoptosis Late in Infection

Senecavirus A (SVA), an oncolytic picornavirus used for cancer treatment in humans, has recently emerged as a vesicular disease (VD)-causing agent in swine worldwide. Notably, SVA-induced VD is indistinguishable from foot-and-mouth disease (FMD) and other high-consequence VDs of pigs. Here we invest...

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Detalles Bibliográficos
Autores principales: Fernandes, Maureen H. V., Maggioli, Mayara F., Otta, Jaelin, Joshi, Lok R., Lawson, Steve, Diel, Diego G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424860/
https://www.ncbi.nlm.nih.gov/pubmed/30918505
http://dx.doi.org/10.3389/fimmu.2019.00363