Repurposed Biguanide Drugs in Glioblastoma Exert Antiproliferative Effects via the Inhibition of Intracellular Chloride Channel 1 Activity

The lack of in-depth knowledge about the molecular determinants of glioblastoma (GBM) occurrence and progression, combined with few effective and BBB crossing-targeted compounds represents a major challenge for the discovery of novel and efficacious drugs for GBM. Among relevant molecular factors co...

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Detalles Bibliográficos
Autores principales: Barbieri, Federica, Verduci, Ivan, Carlini, Valentina, Zona, Gianluigi, Pagano, Aldo, Mazzanti, Michele, Florio, Tullio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424887/
https://www.ncbi.nlm.nih.gov/pubmed/30918838
http://dx.doi.org/10.3389/fonc.2019.00135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424887/
https://www.ncbi.nlm.nih.gov/pubmed/30918838
http://dx.doi.org/10.3389/fonc.2019.00135

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