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CDP-choline accumulation in breast and colorectal cancer cells treated with a GSK-3-targeting inhibitor

PURPOSE: Glycogen synthase kinase 3 (GSK3) is a key controlling element of many cellular processes including cell-cycle progression and recent studies suggest that GSK3 is a potential anticancer target. Changes in glucose metabolism associated with GSK3 inhibition may impact on lipid synthesis, whil...

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Detalles Bibliográficos
Autores principales: Phyu, Su Myat, Tseng, Chih-Chung, Smith, Tim Andrew Davies
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424927/
https://www.ncbi.nlm.nih.gov/pubmed/30446846
http://dx.doi.org/10.1007/s10334-018-0719-3