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von Hippel-Lindau mutants in renal cell carcinoma are regulated by increased expression of RSUME

Renal cell carcinoma (RCC) is the major cause of death among patients with von Hippel-Lindau (VHL) disease. Resistance to therapies targeting tumor angiogenesis opens the question about the underlying mechanisms. Previously we have described that RWDD3 or RSUME (RWD domain-containing protein SUMO En...

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Detalles Bibliográficos
Autores principales: Tedesco, Lucas, Elguero, Belén, Pacin, David Gonilski, Senin, Sergio, Pollak, Cora, Garcia Marchiñena, Patricio A., Jurado, Alberto M., Isola, Mariana, Labanca, María J., Palazzo, Martin, Yankilevich, Patricio, Fuertes, Mariana, Arzt, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424967/
https://www.ncbi.nlm.nih.gov/pubmed/30890701
http://dx.doi.org/10.1038/s41419-019-1507-3