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Keratinocyte differentiation promotes ER stress-dependent lysosome biogenesis

Keratinocytes maintain epidermal integrity through cellular differentiation. This process enhances intraorganelle digestion in keratinocytes to sustain nutritional and calcium-ionic stresses observed in upper skin layers. However, the molecular mechanisms governing keratinocyte differentiation and c...

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Detalles Bibliográficos
Autores principales: Mahanty, Sarmistha, Dakappa, Shruthi Shirur, Shariff, Rezwan, Patel, Saloni, Swamy, Mruthyunjaya Mathapathi, Majumdar, Amitabha, Setty, Subba Rao Gangi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425001/
https://www.ncbi.nlm.nih.gov/pubmed/30890691
http://dx.doi.org/10.1038/s41419-019-1478-4