Cargando…
Keratinocyte differentiation promotes ER stress-dependent lysosome biogenesis
Keratinocytes maintain epidermal integrity through cellular differentiation. This process enhances intraorganelle digestion in keratinocytes to sustain nutritional and calcium-ionic stresses observed in upper skin layers. However, the molecular mechanisms governing keratinocyte differentiation and c...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425001/ https://www.ncbi.nlm.nih.gov/pubmed/30890691 http://dx.doi.org/10.1038/s41419-019-1478-4 |