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Keratinocyte differentiation promotes ER stress-dependent lysosome biogenesis
Keratinocytes maintain epidermal integrity through cellular differentiation. This process enhances intraorganelle digestion in keratinocytes to sustain nutritional and calcium-ionic stresses observed in upper skin layers. However, the molecular mechanisms governing keratinocyte differentiation and c...
Autores principales: | Mahanty, Sarmistha, Dakappa, Shruthi Shirur, Shariff, Rezwan, Patel, Saloni, Swamy, Mruthyunjaya Mathapathi, Majumdar, Amitabha, Setty, Subba Rao Gangi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425001/ https://www.ncbi.nlm.nih.gov/pubmed/30890691 http://dx.doi.org/10.1038/s41419-019-1478-4 |
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