Burden of unique and low prevalence somatic mutations correlates with cancer survival

Tumor mutational burden correlates with improved survival and immunotherapy response in some malignancies, and with tumor aggressiveness in others. To study the link between mutational burden and survival, we analyzed survival effects of tumor exonic missense mutation burden (TEMMB) across 6947 spec...

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Detalles Bibliográficos
Autores principales: Klebanov, Nikolai, Artomov, Mykyta, Goggins, William B., Daly, Emma, Daly, Mark J., Tsao, Hensin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425006/
https://www.ncbi.nlm.nih.gov/pubmed/30890735
http://dx.doi.org/10.1038/s41598-019-41015-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425006/
https://www.ncbi.nlm.nih.gov/pubmed/30890735
http://dx.doi.org/10.1038/s41598-019-41015-5

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