Genome-scale Capture C promoter interactions implicate effector genes at GWAS loci for bone mineral density

Osteoporosis is a devastating disease with an essential genetic component. GWAS have discovered genetic signals robustly associated with bone mineral density (BMD), but not the precise localization of effector genes. Here, we carry out physical and direct variant to gene mapping in human mesenchymal...

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Detalles Bibliográficos
Autores principales: Chesi, Alessandra, Wagley, Yadav, Johnson, Matthew E., Manduchi, Elisabetta, Su, Chun, Lu, Sumei, Leonard, Michelle E., Hodge, Kenyaita M., Pippin, James A., Hankenson, Kurt D., Wells, Andrew D., Grant, Struan F. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425012/
https://www.ncbi.nlm.nih.gov/pubmed/30890710
http://dx.doi.org/10.1038/s41467-019-09302-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425012/
https://www.ncbi.nlm.nih.gov/pubmed/30890710
http://dx.doi.org/10.1038/s41467-019-09302-x

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