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Oxymatrine and its metabolite matrine contribute to the hepatotoxicity induced by radix Sophorae tonkinensis in mice

Previous studies by our group demonstrated that radix Sophorae tonkinensis could induce hepatotoxicity. However, it remains unclear which components of this herb may be responsible for its hepatotoxicity. The present study aimed to investigate the hepatic toxicity of treatment with matrine (MT) and...

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Detalles Bibliográficos
Autores principales: Gu, Yingmin, Lu, Jinyao, Sun, Wei, Jin, Ruomin, Ohira, Toko, Zhang, Zean, Tian, Xuesong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425122/
https://www.ncbi.nlm.nih.gov/pubmed/30906440
http://dx.doi.org/10.3892/etm.2019.7237