Dynamic Methylation of an L1 Transduction Family during Reprogramming and Neurodifferentiation

The retrotransposon LINE-1 (L1) is a significant source of endogenous mutagenesis in humans. In each individual genome, a few retrotransposition-competent L1s (RC-L1s) can generate new heritable L1 insertions in the early embryo, primordial germ line, and germ cells. L1 retrotransposition can also o...

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Detalles Bibliográficos
Autores principales: Salvador-Palomeque, Carmen, Sanchez-Luque, Francisco J., Fortuna, Patrick R. J., Ewing, Adam D., Wolvetang, Ernst J., Richardson, Sandra R., Faulkner, Geoffrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425141/
https://www.ncbi.nlm.nih.gov/pubmed/30692270
http://dx.doi.org/10.1128/MCB.00499-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425141/
https://www.ncbi.nlm.nih.gov/pubmed/30692270
http://dx.doi.org/10.1128/MCB.00499-18

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