Cx43 Inhibition Attenuates Sepsis-Induced Intestinal Injury via Downregulating ROS Transfer and the Activation of the JNK1/Sirt1/FoxO3a Signaling Pathway

Intestinal injury has long been considered to play a crucial role in the pathophysiology of sepsis and has even been characterized as the “motor” of it. Thus, we explored the effects of connexin43 (Cx43) on sepsis-induced intestinal injury in order to provide potential therapeutic strategies. Rat ce...

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Detalles Bibliográficos
Autores principales: Zou, Zhaowei, Liu, Bin, Zeng, Lisi, Yang, Xianzi, Huang, Renli, Wu, Cheng, Zhu, Huijuan, Gao, Yi, Yuan, Dongdong, Yu, Jinlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425293/
https://www.ncbi.nlm.nih.gov/pubmed/30948926
http://dx.doi.org/10.1155/2019/7854389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425293/
https://www.ncbi.nlm.nih.gov/pubmed/30948926
http://dx.doi.org/10.1155/2019/7854389

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