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A Case Report of Massive Acetaminophen Poisoning Treated with a Novel “Triple Therapy”: N-Acetylcysteine, 4-Methylpyrazole, and Hemodialysis

Massive acetaminophen (N-acetyl-p-aminophenol; APAP) ingestion is characterized by a rapid onset of mitochondrial dysfunction, including metabolic acidosis, lactemia, and altered mental status without hepatotoxicity which may not respond to the standard doses of N-acetylcysteine (NAC). A 64-year-old...

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Detalles Bibliográficos
Autores principales: Kiernan, Emily A., Fritzges, Julie A., Henry, Kathryn A., Katz, Kenneth D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425342/
https://www.ncbi.nlm.nih.gov/pubmed/30956824
http://dx.doi.org/10.1155/2019/9301432