Pharmacokinetic Study and Tissue Distribution of Lorlatinib in Mouse Serum and Tissue Samples by Liquid Chromatography-Mass Spectrometry

In the present study, we developed and validated a rapid and simple liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the determination of lorlatinib in mouse serum and tissue samples, and such a method was successfully applied to investigate the pharmacokinetic study and tissue d...

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Detalles Bibliográficos
Autores principales: Chen, Wei, Shi, Yafei, Qi, Shuya, Zhou, Haiyan, Li, Chunyu, Jin, Dujia, Li, Guohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425379/
https://www.ncbi.nlm.nih.gov/pubmed/30949374
http://dx.doi.org/10.1155/2019/7574369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425379/
https://www.ncbi.nlm.nih.gov/pubmed/30949374
http://dx.doi.org/10.1155/2019/7574369

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