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EF24 Suppresses Cholangiocellular Carcinoma Progression, Inhibits STAT3 Phosphorylation, and Induces Apoptosis via ROS-Mediated Oxidative Stress

Therapeutic options for advanced stage cholangiocellular carcinoma (CCC) are very limited as of today and patients carry an exceptionally poor overall prognosis. In recent years, increasing evidence has been accumulated to suggest that malignant cells widely show increased intrinsic ROS levels and e...

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Detalles Bibliográficos
Autores principales: Bisht, Savita, Nolting, Jens, Wenzel, Jörg, Brossart, Peter, Feldmann, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425401/
https://www.ncbi.nlm.nih.gov/pubmed/30949204
http://dx.doi.org/10.1155/2019/8701824