Pancreatic cancer-initiating cell exosome message transfer into noncancer-initiating cells: the importance of CD44v6 in reprogramming

BACKGROUND: Cancer-initiating cell (CIC) exosomes (CIC-TEX) are suggested reprogramming Non-CIC. Mode of message transfer and engagement of CIC-markers being disputed, we elaborated the impact of CD44v6 and Tspan8 on the response of Non-CIC. METHODS: Non-metastasizing CD44v6- and Tspan8-knockdown (k...

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Detalles Bibliográficos
Autores principales: Wang, Zhe, Sun, Hanxue, Provaznik, Jan, Hackert, Thilo, Zöller, Margot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425561/
https://www.ncbi.nlm.nih.gov/pubmed/30890157
http://dx.doi.org/10.1186/s13046-019-1129-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425561/
https://www.ncbi.nlm.nih.gov/pubmed/30890157
http://dx.doi.org/10.1186/s13046-019-1129-8

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