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Altered PGE2-EP2 is associated with an excessive immune response in HBV-related acute-on-chronic liver failure

BACKGROUND AND AIMS: Prostaglandin E receptor 2 (EP2) is an immune modulatory molecule that regulates the balance of immunity. Here we investigated the role of EP2 in immune dysregulation in patients with acute-on-chronic liver failure (ACLF). METHODS: Plasma Progstaglandin E2 (PGE2) levels and EP2...

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Detalles Bibliográficos
Autores principales: Wang, Yunyun, Chen, Chao, Qi, Jinjin, Wu, Fengtian, Guan, Jun, Chen, Zhi, Zhu, Haihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425563/
https://www.ncbi.nlm.nih.gov/pubmed/30890164
http://dx.doi.org/10.1186/s12967-019-1844-0