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Longitudinal heterogeneity in glioblastoma: moving targets in recurrent versus primary tumors
BACKGROUND: Molecularly targeted therapies using receptor inhibitors, small molecules or monoclonal antibodies are routinely applied in oncology. Verification of target expression should be mandatory prior to initiation of therapy, yet, determining the expression status is most challenging in recurr...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425567/ https://www.ncbi.nlm.nih.gov/pubmed/30894200 http://dx.doi.org/10.1186/s12967-019-1846-y |