PAGA: graph abstraction reconciles clustering with trajectory inference through a topology preserving map of single cells

Single-cell RNA-seq quantifies biological heterogeneity across both discrete cell types and continuous cell transitions. Partition-based graph abstraction (PAGA) provides an interpretable graph-like map of the arising data manifold, based on estimating connectivity of manifold partitions (https://gi...

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Detalles Bibliográficos
Autores principales: Wolf, F. Alexander, Hamey, Fiona K., Plass, Mireya, Solana, Jordi, Dahlin, Joakim S., Göttgens, Berthold, Rajewsky, Nikolaus, Simon, Lukas, Theis, Fabian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425583/
https://www.ncbi.nlm.nih.gov/pubmed/30890159
http://dx.doi.org/10.1186/s13059-019-1663-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425583/
https://www.ncbi.nlm.nih.gov/pubmed/30890159
http://dx.doi.org/10.1186/s13059-019-1663-x

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